If you think you need surgery to lose the weight that is plaguing you, then you may want to wait a while. Science is always evolving. Now they have discovery a new chemical made in the gut called NAPE. This chemical triggers the brain to stop eating.
NAPE concentrated in the hypothalamus, an important brain structure known to regulate hunger, and inhibited neurons that stimulate appetite, they said.
When the rodents were given extra NAPE for five days, they animals ate less and lost weight, the researchers said.
With obesity on the rise in many parts of the world as people eat fattier diets and get less exercise, scientists are eager to find new ways to combat the problem. These findings could help guide efforts to create better drugs to suppress appetite and reduce obesity, the researchers said.
“Clearly what we have in mind is trying to find new approaches that regulate food intake. And this may be a new pathway that one could target to treat obesity,” Shulman said in a telephone interview.
“We’re now doing the fat-feeding studies in humans to see if we get a similar increase in plasma (blood) NAPE concentrations following a fatty meal,” Shulman added.
Scientists are working toward a greater understanding of how the body tells the brain to control food intake. Hormones such as leptin that help regulate this system have proven disappointing when examined as human weight-loss treatments (source).
Research is the portal to the future. However, this chemical may be years away from the shelf. Until then, find ways to change your diet and exercise from the inside out.
Adria Ali
(CES, PES, CPT, BS)
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